SNORA14A inhibits hepatoblastoma cell proliferation by regulating SDHB-mediated succinate metabolism
Abstract Hepatoblastoma (HB) is the most common paediatric liver malignancy.Dysregulation of small nucleolar RNAs (snoRNAs) is a critical inducer of tumour initiation and progression.However, the association between snoRNAs and HB remains unknown.Here, we conducted snoRNA expression profiling in HB by snoRNA sequencing and identified a decreased le